Aura Biosciences, Inc. reported significant financial developments in its latest 10-Q filing for the quarter ending September 30, 2024. The company, which focuses on developing precision therapies for solid tumors, experienced a decrease in cash and cash equivalents, which fell to $25.4 million from $41.1 million at the end of 2023. Marketable securities also declined to $149.0 million from $185.1 million, contributing to a total asset reduction from $255.1 million to $205.3 million over the same period. Total current liabilities increased to $14.7 million, up from $12.4 million.

The company reported a net loss of $21.0 million for the third quarter of 2024, compared to a loss of $18.5 million in the same quarter of 2023. For the nine months ended September 30, 2024, the net loss was $61.1 million, an increase from $54.3 million in the prior year. Operating expenses for the third quarter rose to $23.2 million, up from $20.5 million in 2023, driven by increased research and development costs, which reached $17.0 million, compared to $15.4 million in the previous year.

The company’s accumulated deficit increased to $348.4 million as of September 30, 2024, reflecting ongoing operational losses. Despite these challenges, Aura Biosciences raised $99.0 million in gross proceeds from a follow-on offering in November 2023, issuing 11 million shares at $9.00 each. The company also filed a new shelf registration statement in March 2024 for an aggregate offering price of $350.0 million.

Strategically, Aura is advancing its lead candidate, bel-sar, which is currently in a global Phase 3 trial for treating small choroidal melanoma. The trial aims to provide a vision-sparing option for patients and has received Orphan Drug Designation from the FDA. The company is also exploring bel-sar for additional indications, including bladder cancer, with a Phase 1 trial ongoing.

As of September 30, 2024, Aura had approximately $174.4 million in cash and marketable securities, which it expects will fund operations into the second half of 2026. However, the company anticipates substantial increases in expenses as it continues to develop bel-sar and other product candidates, with no revenue generated from product sales to date. The reliance on external funding remains critical for the company’s future operations and clinical development efforts.

About Aura Biosciences, Inc.

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